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1

Pyroglutamate Formation Influences Solubility and Amyloidogenicity of Amyloid Peptides

Schlenzig, Dagmar, Manhart, Susanne, Cinar, Yeliz, Kleinschmidt, Martin, Hause, Gerd, Willbold, Dieter, Funke, Susanne Aileen, Schilling, Stephan, Demuth, Hans-Ulrich

Journal:

Year:

2009

Language:

english

File:

PDF, 910 KB

english, 2009

2

Safety and pharmacokinetics of the orally available antiprionic compound PRIâ002: A single and multiple ascending dose phase I study

Kutzsche, Janine, JÃ¼rgens, Dagmar, Willuweit, Antje, Adermann, Knut, Fuchs, Carola, Simons, Stefanie, Windisch, Manfred, HÃ¼mpel, Michael, Rossberg, Wolfgang, Wolzt, Michael, Willbold, Dieter

Journal:

Alzheimer s & Dementia Translational Research & Clinical Interventions

Year:

2020

Language:

english

File:

PDF, 848 KB

english, 2020

3

Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae “Short” Light, Oxygen, Voltage (LOV) Protein Family: Implications for the Design of LOV-Based Optogenetic Tools

Rani, Raj, Jentzsch, Katrin, Lecher, Justin, Hartmann, Rudolf, Willbold, Dieter, Jaeger, Karl-Erich, Krauss, Ulrich

Journal:

Year:

2013

Language:

english

File:

PDF, 4.00 MB

english, 2013

4

Relaxation Behavior Study of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles at Ultralow and Ultrahigh Magnetic Fields

Wang, Wei, Dong, Hui, Pacheco, Victor, Willbold, Dieter, Zhang, Yi, Offenhaeusser, Andreas, Hartmann, Rudolf, Weirich, Thomas E., Ma, Peixiang, Krause, Hans-Joachim, Gu, Zhongwei

Journal:

Journal of Physical Chemistry B

Year:

2011

Language:

english

File:

PDF, 4.56 MB

english, 2011

5

Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy

Röllen, Katrin, Granzin, Joachim, Panwalkar, Vineet, Arinkin, Vladimir, Rani, Raj, Hartmann, Rudolf, Krauss, Ulrich, Jaeger, Karl-Erich, Willbold, Dieter, Batra-Safferling, Renu

Journal:

Journal of Molecular Biology

Year:

2016

Language:

english

File:

PDF, 2.56 MB

english, 2016

6

Fibril structure of amyloid-ß(1-42) by cryoelectron microscopy

Gremer, Lothar, Schölzel, Daniel, Schenk, Carla, Reinartz, Elke, Labahn, Jörg, Ravelli, Raimond B. G., Tusche, Markus, Lopez-Iglesias, Carmen, Hoyer, Wolfgang, Heise, Henrike, Willbold, Dieter, Schröd

Journal:

Year:

2017

Language:

english

File:

PDF, 3.30 MB

english, 2017

7

Relevance of N-terminal residues for amyloid-β binding to platelet integrin α IIb β 3 , integrin outside-in signaling and amyloid-β fibril formation

Donner, Lili, Gremer, Lothar, Ziehm, Tamar, Gertzen, Christoph G.W., Gohlke, Holger, Willbold, Dieter, Elvers, Margitta

Journal:

Cellular Signalling

Year:

2018

Language:

english

File:

PDF, 6.71 MB

english, 2018

8

Amino Terminal Region of Dengue Virus NS4A Cytosolic Domain Binds to Highly Curved Liposomes

Hung, Yu-Fu, Schwarten, Melanie, Hoffmann, Silke, Willbold, Dieter, Sklan, Ella, Koenig, Bernd

Journal:

Year:

2015

Language:

english

File:

PDF, 618 KB

english, 2015

9

Integrated NMR, Fluorescence and MD Benchmark Study of Protein Mechanics and Hydrodynamics

Möckel, Christina, Kubiak, Jakub, Schillinger, Oliver, Kuehnemuth, Ralf, Della Corte, Dennis, Schröder, Gunnar F., Willbold, Dieter, Strodel, Birgit, Seidel, Claus A.M., Neudecker, Philipp

Journal:

Journal of Physical Chemistry B

Year:

2018

Language:

english

File:

PDF, 27.94 MB

english, 2018

10

Mirror-image Phage Display: Aiming at the Mirror

Katja Wiesehan, Dieter Willbold

Journal:

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

11

Selection of D-Amino-Acid Peptides That Bind to Alzheimer's Disease Amyloid Peptide Aβ1–42 by Mirror Image Phage Display

Katja Wiesehan, Katrin Buder, Reinhold P. Linke, Stephan Patt, Matthias Stoldt, Eberhard Unger, Bettina Schmitt, Enrico Bucci, Dieter Willbold

Journal:

Year:

2003

Language:

english

File:

PDF, 171 KB

english, 2003

12

An Indole-Binding Site is a Major Determinant of the Ligand Specificity of the GABA Type A Receptor-Associated Protein GABARAP

Yvonne Thielmann, Jeannine Mohrlüder, Bernd W. Koenig, Thomas Stangler, Rudolf Hartmann, Karin Becker, Hans-Dieter Höltje, Dieter Willbold

Journal:

Year:

2008

Language:

english

File:

PDF, 869 KB

english, 2008

13

Cover Picture: An Indole-Binding Site is a Major Determinant of the Ligand Specificity of the GABA Type A Receptor-Associated Protein GABARAP (ChemBioChem 11/2008)

Yvonne Thielmann, Jeannine Mohrlüder, Bernd W. Koenig, Thomas Stangler, Rudolf Hartmann, Karin Becker, Hans-Dieter Höltje, Dieter Willbold

Journal:

Year:

2008

Language:

english

File:

PDF, 644 KB

english, 2008

14

Preparation of a Functional GABARAP–Lipid Conjugate in Nanodiscs and its Investigation by Solution NMR Spectroscopy

Peixiang Ma, Dr. Jeannine Mohrlüder, Melanie Schwarten , Dr. Matthias Stoldt , Sameer K. Singh, Dr. Rudolf Hartmann, Dr. Victor Pacheco , Prof. Dr. Dieter Willbold

Journal:

Year:

2010

Language:

english

File:

PDF, 420 KB

english, 2010

15

Selection of D-Amino-Acid Peptides that Bind to Alzheimer′s Disease Amyloid Peptide Aβ1-42 by Mirror Image Phage Display.

Katja Wiesehan, Katrin Buder, Reinhold P. Linke, Stephan Patt, Matthias Stoldt, Eberhard Unger, Bettina Schmitt, Enrico Bucci, Dieter Willbold

Journal:

Year:

2003

File:

PDF, 54 KB

2003

16

Mirror-Image Phage Display: Aiming at the Mirror

Katja Wiesehan, Dieter Willbold

Journal:

Year:

2003

File:

PDF, 49 KB

2003

17

Reduction of Alzheimer’s Disease Amyloid Plaque Load in Transgenic Mice by D3, a D-Enantiomeric Peptide Identified by Mirror Image Phage Display

Thomas van Groen, Katja Wiesehan, Susanne A. Funke, Inga Kadish, Luitgard Nagel-Steger, Dieter Willbold

Journal:

Year:

2008

Language:

english

File:

PDF, 493 KB

english, 2008

18

In vitro and in vivo Staining Characteristics of Small, Fluorescent, Aβ42-Binding D-Enantiomeric Peptides in Transgenic AD Mouse Models

Thomas van Groen, Inga Kadish, Katja Wiesehan, Susanne A. Funke, Dieter Willbold

Journal:

Year:

2009

Language:

english

File:

PDF, 584 KB

english, 2009

19

Nonaqueous versus aqueous capillary electrophoresis of α-helical polypeptides: Effect of secondary structure on separation selectivity

Arndt Psurek, Sophie Feuerstein, Dieter Willbold, Gerhard K. E. Scriba

Journal:

ELECTROPHORESIS

Year:

2006

Language:

english

File:

PDF, 335 KB

english, 2006

20

C-Src is required for complex formation between the hepatitis C virus–encoded proteins NS5A and NS5B: A prerequisite for replication

Andreas Pfannkuche, Katrin Büther, Juliane Karthe, Marion Poenisch, Ralf Bartenschlager, Mirko Trilling, Hartmut Hengel, Dieter Willbold, Dieter Häussinger, Johannes Georg Bode

Journal:

Year:

2011

Language:

english

File:

PDF, 901 KB

english, 2011

21

Nanodiscs allow the use of integral membrane proteins as analytes in surface plasmon resonance studies

Julian M. Glück, Bernd W. Koenig, Dieter Willbold

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 388 KB

english, 2011

22

Purification of recombinantly expressed and cytotoxic human amyloid-beta peptide 1–42

Katja Wiesehan, Susanne Aileen Funke, Miriam Fries, Dieter Willbold

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 290 KB

english, 2007

23

Solution structure of human immunodeficiency virus type 1 Vpr(13–33) peptide in micelles

Andrea Engler, Thomas Stangler, Dieter Willbold

Journal:

Year:

2001

Language:

english

File:

PDF, 568 KB

english, 2001

24

Structure of human immunodeficiency virus type 1 Vpr(34–51) peptide in micelle containing aqueous solution

Andrea Engler, Thomas Stangler, Dieter Willbold

Journal:

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

25

Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopy

Lars Briese, Dieter Willbold

Journal:

BMC Structural Biology

Year:

2003

Language:

english

File:

PDF, 1.21 MB

english, 2003

26

Potential role of HIV-1 Nef and human M6B in HIV-associated neurological disorders

Jessica Moetter, Silke Hoffmann, Esther Jonas, Dieter Willbold

Journal:

Year:

2010

Language:

english

File:

PDF, 164 KB

english, 2010

27

Role of the Cys 2-Cys 10 disulfide bond for the structure, stability, and folding kinetics of ribonuclease T1

Lorenz M. Mayr, Dieter Willbold, Olfert Landt, Franz X. Schmidm

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 2.13 MB

english, 1994

28

Comparative modeling of human NSF reveals a possible binding mode of GABARAP and GATE-16

Yvonne Thielmann, Oliver H. Weiergräber, Peixiang Ma, Melanie Schwarten, Jeannine Mohrlüder, Dieter Willbold

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 529 KB

english, 2009

29

Structural consequences of phosphorylation of two serine residues in the cytoplasmic domain of HIV-1 VpU

Marc Wittlich, Bernd W. Koenig, Dieter Willbold

Journal:

Journal of Peptide Science

Year:

2008

Language:

english

File:

PDF, 289 KB

english, 2008

30

Binding of phage-displayed HIV-1 tat to TAR RNA in the presence of cyclin T1

Gesa Jonas, Silke Hoffmann, Dieter Willbold

Journal:

Journal of Biomedical Science

Year:

2001

Language:

english

File:

PDF, 1.09 MB

english, 2001

31

Modulation of aggregate size- and shape-distributions of the amyloid-β peptide by a designed β-sheet breaker

Luitgard Nagel-Steger, Borries Demeler, Wolfgang Meyer-Zaika, Katrin Hochdörffer, Thomas Schrader, Dieter Willbold

Journal:

European Biophysics Journal

Year:

2010

Language:

english

File:

PDF, 566 KB

english, 2010

32

Transient reduction of spontaneous neuronal network activity by sublethal amyloid β (1–42) peptide concentrations

Philipp Görtz, Jessica Opatz, Mario Siebler, Susanne Aileen Funke, Dieter Willbold, Christian Lange-Asschenfeldt

Journal:

Journal of Neural Transmission

Year:

2009

Language:

english

File:

PDF, 240 KB

english, 2009

33

Assessment of GABARAP self-association by its diffusion properties

Victor Pacheco, Peixiang Ma, Yvonne Thielmann, Rudolf Hartmann, Oliver H. Weiergräber, Jeannine Mohrlüder, Dieter Willbold

Journal:

Journal of Biomolecular NMR

Year:

2010

Language:

english

File:

PDF, 491 KB

english, 2010

34

Solution structure of the X4 protein coded by the SARS related coronavirus reveals an immunoglobulin like fold and suggests a binding activity to integrin I domains

Karen Hänel, Thomas Stangler, Matthias Stoldt, Dieter Willbold

Journal:

Journal of Biomedical Science

Year:

2006

Language:

english

File:

PDF, 464 KB

english, 2006

35

Resonance assignment of the cyclic nucleotide binding domain from a cyclic nucleotide-gated K+channel in complex with cAMP

Sven Schünke, Kerstin Novak, Matthias Stoldt, U. Benjamin Kaupp, Dieter Willbold

Journal:

Biomolecular NMR Assignments

Year:

2007

Language:

english

File:

PDF, 1.01 MB

english, 2007

36

Sequence-specific1H,13C, and15N resonance assignment of the autophagy-related protein Atg8

Melanie Schwarten, Matthias Stoldt, Jeannine Mohrlüder, Dieter Willbold

Journal:

Biomolecular NMR Assignments

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

37

Resonance assignments of the nucleotide-free wildtype MloK1 cyclic nucleotide-binding domain

Sven Schünke, Justin Lecher, Matthias Stoldt, U. Benjamin Kaupp, Dieter Willbold

Journal:

Biomolecular NMR Assignments

Year:

2010

Language:

english

File:

PDF, 1.67 MB

english, 2010

38

1H,15N and13C resonance assignment of the N-terminal C39 peptidase-like domain of the ABC transporter Haemolysin B (HlyB)

Justin Lecher, Matthias Stoldt, Christian K. W. Schwarz, Sander H. J. Smits, Lutz Schmitt, Dieter Willbold

Journal:

Biomolecular NMR Assignments

Year:

2011

Language:

english

File:

PDF, 170 KB

english, 2011

39

1H,13C, and15N resonance assignment of a 179 residue fragment of hepatitis C virus non-structural protein 5A

Sophie Feuerstein, Zsófia Solyom, Amine Aladağ, Silke Hoffmann, Dieter Willbold, Bernhard Brutscher

Journal:

Biomolecular NMR Assignments

Year:

2011

Language:

english

File:

PDF, 244 KB

english, 2011

40

Purification of recombinantly expressed human cluster determinant 4 cytoplasmic domain

Andrea Preusser, Gesa Jonas, Dieter Willbold

Journal:

Journal of Chromatography B

Year:

2003

Language:

english

File:

PDF, 174 KB

english, 2003

41

Identification of calreticulin as a ligand of GABARAP by phage display screening of a peptide library

Jeannine Mohrlüder, Thomas Stangler, Yvonne Hoffmann, Katja Wiesehan, Anja Mataruga, Dieter Willbold

Journal:

Year:

2007

Language:

english

File:

PDF, 476 KB

english, 2007

42

Structural framework of the GABARAP–calreticulin interface – implications for substrate binding to endoplasmic reticulum chaperones

Yvonne Thielmann, Oliver H. Weiergräber, Jeannine Mohrlüder, Dieter Willbold

Journal:

Year:

2009

Language:

english

File:

PDF, 718 KB

english, 2009

43

Structure and potential function of γ-aminobutyrate type A receptor-associated protein

Jeannine Mohrlüder, Melanie Schwarten, Dieter Willbold

Journal:

Year:

2009

Language:

english

File:

PDF, 486 KB

english, 2009

44

NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles

Marc Wittlich, Bernd W. Koenig, Matthias Stoldt, Holger Schmidt, Dieter Willbold

Journal:

Year:

2009

Language:

english

File:

PDF, 685 KB

english, 2009

45

Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP

Schünke, Sven, Stoldt, Matthias, Novak, Kerstin, Kaupp, U Benjamin, Willbold, Dieter

Journal:

Year:

2009

Language:

english

File:

PDF, 1010 KB

english, 2009

46

Letter to the Editor: Sequence-specific1H,13C and15N resonance assignments of lymphocyte specific kinase unique and SH3 domains

Lars Briese, Silke Hoffmann, Ute Friedrich, Brigitte Biesinger, Dieter Willbold

Journal:

Journal of Biomolecular NMR

Year:

2001

Language:

english

File:

PDF, 45 KB

english, 2001

47

Letter to the Editor: Sequence-specific 1H, 13C and 15N resonance assignments of human GABA receptor associated protein

Thomas Stangler, Lorenz M. Mayr, Andrew J. Dingley, Cornelia Luge, Dieter Willbold

Journal:

Journal of Biomolecular NMR

Year:

2001

Language:

english

File:

PDF, 54 KB

english, 2001

48

Solution structure of the human CD4 (403–419) receptor peptide

Dieter Willbold, Paul Rösch

Journal:

Journal of Biomedical Science

Year:

1996

Language:

english

File:

PDF, 908 KB

english, 1996

49

iHADAMAC: A complementary tool for sequential resonance assignment of globular and highly disordered proteins

Sophie Feuerstein, Michael J. Plevin, Dieter Willbold, Bernhard Brutscher

Journal:

Journal of Magnetic Resonance

Year:

2012

Language:

english

File:

PDF, 557 KB

english, 2012

50

Counting of single prion particles bound to a capture-antibody surface (surface-FIDA)

Eva Birkmann, Franziska Henke, Nicole Weinmann, Christian Dumpitak, Martin Groschup, Aileen Funke, Dieter Willbold, Detlev Riesner

Journal:

Veterinary Microbiology

Year:

2007

Language:

english

File:

PDF, 776 KB

english, 2007